High-throughput electron tomography identifies centriole over-elongation as an early event in plasma cell disorders

Plasma cell disorders are clonal outgrowths of pre-malignant or malignant plasma cells, characterized by extensive chromosomal aberrations. Centrosome abnormalities are a major driver of chromosomal instability in cancer but their origin, incidence, and composition in primary tumor cells is poorly u...

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Detalles Bibliográficos
Autores principales: Köhrer, Sebastian, Dittrich, Tobias, Schorb, Martin, Weinhold, Niels, Haberbosch, Isabella, Börmel, Mandy, Pajor, Gabor, Goldschmidt, Hartmut, Müller-Tidow, Carsten, Raab, Marc S., John, Lukas, Seckinger, Anja, Brobeil, Alexander, Dreger, Peter, Tornóczky, Tamás, Pajor, László, Hegenbart, Ute, Schönland, Stefan O., Schwab, Yannick, Krämer, Alwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681902/
https://www.ncbi.nlm.nih.gov/pubmed/37821581
http://dx.doi.org/10.1038/s41375-023-02056-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681902/
https://www.ncbi.nlm.nih.gov/pubmed/37821581
http://dx.doi.org/10.1038/s41375-023-02056-y

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