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SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes undetectable in upper airways after a few days or weeks postinfection. Here we used a model of viral infection in macaques to address whether SARS-CoV-2 persists in the body and which mechanisms regulate its persisten...

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Detalles Bibliográficos
Autores principales: Huot, Nicolas, Planchais, Cyril, Rosenbaum, Pierre, Contreras, Vanessa, Jacquelin, Beatrice, Petitdemange, Caroline, Lazzerini, Marie, Beaumont, Emma, Orta-Resendiz, Aurelio, Rey, Félix A., Reeves, R. Keith, Le Grand, Roger, Mouquet, Hugo, Müller-Trutwin, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681903/
https://www.ncbi.nlm.nih.gov/pubmed/37919524
http://dx.doi.org/10.1038/s41590-023-01661-4