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Inhibition of the mTORC1 pathway alleviates adipose tissue fibrosis

BACKGROUND: Adipose fibrosis is a major factor of adipose dysfunction, which causes metabolic dysfunction during obesity, but its molecular mechanisms are poorly understood. This study investigated the role and potential mechanisms of mTORC1 in obesity-induced adipose fibrosis. METHODS: ob/ob mice w...

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Detalles Bibliográficos
Autores principales: Gong, Sa, Li, Chang, Leng, Qingyang, Liu, Chongxiao, Zhu, Yi, Zhang, Hongli, Li, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10681937/
https://www.ncbi.nlm.nih.gov/pubmed/38034664
http://dx.doi.org/10.1016/j.heliyon.2023.e21526