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ΔNp63α facilitates proliferation and migration, and modulates the chromatin landscape in intrahepatic cholangiocarcinoma cells

p63 plays a crucial role in epithelia-originating tumours; however, its role in intrahepatic cholangiocarcinoma (iCCA) has not been completely explored. Our study revealed the oncogenic properties of p63 in iCCA and identified the major expressed isoform as ΔNp63α. We collected iCCA clinical data fr...

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Detalles Bibliográficos
Autores principales: Peng, Anghui, Lin, Xiaowen, Yang, Quanli, Sun, Yihao, Chen, Ruiyan, Liu, Bing, Yu, Xinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682000/
https://www.ncbi.nlm.nih.gov/pubmed/38012140
http://dx.doi.org/10.1038/s41419-023-06309-7