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Long noncoding RNA NONHSAT160169.1 promotes resistance via hsa-let-7c-3p/SOX2 axis in gastric cancer

In clinical trials involving patients with HER2 (ERBB2 receptor tyrosine kinase 2) positive gastric cancer, the efficacy of the HER2-targeted drug lapatinib has proven to be disappointingly poor. Under the persistent pressure exerted by targeted drug therapy, a subset of tumor cells exhibit acquired...

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Detalles Bibliográficos
Autores principales: Zhao, Xuan, Xu, Zijian, Meng, Bi, Ren, Tong, Wang, Xu, Hou, Rui, Li, Sijin, Ma, Wen, Liu, Dan, Zheng, Junnian, Shi, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682003/
https://www.ncbi.nlm.nih.gov/pubmed/38012281
http://dx.doi.org/10.1038/s41598-023-47961-5