Ex-vivo CS1-OKT3 dual specific bivalent antibody-armed effector T cells mediate cellular immunity against multiple myeloma

Bispecific T cell engaging antibodies (bsAbs) have emerged as novel and powerful therapeutic agents for redirecting T cells towards antigen-specific tumor killing. The cell surface glycoprotein and SLAM family member, CS1, exhibits stable and high-level expression on malignant plasma cells including...

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Detalles Bibliográficos
Autores principales: Awuah, Dennis, Li, Lin, Williams, Lindsay, Urak, Ryan, Kujawski, Maciej, Forman, Stephen J., Shively, John E., Wang, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682018/
https://www.ncbi.nlm.nih.gov/pubmed/38012196
http://dx.doi.org/10.1038/s41598-023-47115-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682018/
https://www.ncbi.nlm.nih.gov/pubmed/38012196
http://dx.doi.org/10.1038/s41598-023-47115-7

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