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Ex-vivo CS1-OKT3 dual specific bivalent antibody-armed effector T cells mediate cellular immunity against multiple myeloma
Bispecific T cell engaging antibodies (bsAbs) have emerged as novel and powerful therapeutic agents for redirecting T cells towards antigen-specific tumor killing. The cell surface glycoprotein and SLAM family member, CS1, exhibits stable and high-level expression on malignant plasma cells including...
Autores principales: | Awuah, Dennis, Li, Lin, Williams, Lindsay, Urak, Ryan, Kujawski, Maciej, Forman, Stephen J., Shively, John E., Wang, Xiuli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682018/ https://www.ncbi.nlm.nih.gov/pubmed/38012196 http://dx.doi.org/10.1038/s41598-023-47115-7 |
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