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Efficacy and safety of 5-hydroxytryptamine-3 (5-HT3) receptor antagonists in augmentation with selective serotonin reuptake inhibitors (SSRIs) in the treatment of moderate to severe obsessive–compulsive disorder: a systematic review and meta-analysis of randomized clinical trials

Obsessive–compulsive disorder (OCD) is the fourth most common mental disorder, and selective serotonin reuptake inhibitors (SSRIs) are the cornerstone of its pharmacological treatment. About 40–60% of the cases are treatment-refractory, and this makes searching for second-line treatment necessary. 5...

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Detalles Bibliográficos
Autores principales: Eissazade, Negin, Mosavari, Hesam, Eghdami, Shayan, Boroon, Mahsa, Ashrafi, Faria, Shalbafan, Mohammadreza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682036/
https://www.ncbi.nlm.nih.gov/pubmed/38012263
http://dx.doi.org/10.1038/s41598-023-47931-x