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USP10 suppresses ABCG2-induced malignant characteristics of doxorubicin-resistant thyroid cancer by inhibiting PI3K/AKT pathway

Doxorubicin (DOX) is the most extensively used drug in the chemotherapy of thyroid cancer (TC). However, the existence of DOX resistance is not conducive to TC treatment. Here, we investigated the role of USP10 in DOX-resistant TC and explored the underlying molecular mechanism. CCK-8 assay was used...

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Detalles Bibliográficos
Autores principales: Sun, Jianwei, Xiang, Qian, Ding, Ding, Yan, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682060/
https://www.ncbi.nlm.nih.gov/pubmed/37919637
http://dx.doi.org/10.1007/s10863-023-09986-3