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In vitro pharmacological characterization of standard and new lysophosphatidic acid receptor antagonists using dynamic mass redistribution assay

Lysophosphatidic acid (LPA) is a bioactive phospholipid that acts as an agonist of six G protein-coupled receptors named LPA receptors (LPA(1-6)). LPA elicits diverse intracellular events and modulates several biological functions, including cell proliferation, migration, and invasion. Overactivatio...

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Detalles Bibliográficos
Autores principales: Ruzza, C., Argentieri, M., Ferrari, F., Armani, E., Trevisani, M., Marchini, G., Calo’, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682101/
https://www.ncbi.nlm.nih.gov/pubmed/38035009
http://dx.doi.org/10.3389/fphar.2023.1267414