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PARP-1 is a transcriptional rheostat of metabolic and bivalent genes during development

PARP-1 participates in various cellular processes, including gene regulation. In Drosophila, PARP-1 mutants undergo developmental arrest during larval-to-pupal transition. In this study, we investigated PARP-1 binding and its transcriptional regulatory role at this stage. Our findings revealed that...

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Detalles Bibliográficos
Autores principales: Bamgbose, Gbolahan, Tulin, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682175/
https://www.ncbi.nlm.nih.gov/pubmed/38012002
http://dx.doi.org/10.26508/lsa.202302369