Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2)

Enzymatic breakdown of sphingomyelin by sphingomyelinase (SMase) is the main source of the membrane lipids, ceramides, which are involved in many cellular physiological processes. However, the full-length structure of human neutral SMase has not been resolved; therefore, its catalytic mechanism rema...

Descripción completa

Detalles Bibliográficos
Autores principales: Yi, Jingbo, Qi, Boya, Yin, Jian, Li, Ruochong, Chen, Xudong, Hu, Junhan, Li, Guohui, Zhang, Sensen, Zhang, Yuebin, Yang, Maojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682184/
https://www.ncbi.nlm.nih.gov/pubmed/38012235
http://dx.doi.org/10.1038/s41467-023-43580-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682184/
https://www.ncbi.nlm.nih.gov/pubmed/38012235
http://dx.doi.org/10.1038/s41467-023-43580-w

Ejemplares similares