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Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2)
Enzymatic breakdown of sphingomyelin by sphingomyelinase (SMase) is the main source of the membrane lipids, ceramides, which are involved in many cellular physiological processes. However, the full-length structure of human neutral SMase has not been resolved; therefore, its catalytic mechanism rema...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682184/ https://www.ncbi.nlm.nih.gov/pubmed/38012235 http://dx.doi.org/10.1038/s41467-023-43580-w |