Generation and ex vivo culture of murine and human pancreatic ductal adenocarcinoma tissue slice explants

Traditional 2D/3D co-culture models typically do not reflect the cellular heterogeneity of pancreatic ductal adenocarcinoma (PDAC) tumors, while in vivo models can be slow and ill-suited to mechanistic investigations. Here, we present a protocol for culturing murine PDAC explants and a corresponding...

Descripción completa

Detalles Bibliográficos
Autores principales: Decker-Farrell, Amanda R., Ma, Alice, Li, Fangda, Muir, Alexander, Olive, Kenneth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682255/
https://www.ncbi.nlm.nih.gov/pubmed/37950862
http://dx.doi.org/10.1016/j.xpro.2023.102711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682255/
https://www.ncbi.nlm.nih.gov/pubmed/37950862
http://dx.doi.org/10.1016/j.xpro.2023.102711

Ejemplares similares