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Deep learning untangles the resistance mechanism of p53 reactivator in lung cancer cells
Tumor suppressor p53 plays a pivotal role in suppressing cancer, so various drugs has been suggested to upregulate its function. However, drug resistance is still the biggest hurdle to be overcome. To address this, we developed a deep learning model called AnoDAN (anomalous gene detection using gene...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682260/ https://www.ncbi.nlm.nih.gov/pubmed/38034356 http://dx.doi.org/10.1016/j.isci.2023.108377 |