Discovery of a non-canonical prototype long-chain monoacylglycerol lipase through a structure-based endogenous reaction intermediate complex

The identification and characterization of enzyme function is largely lacking behind the rapidly increasing availability of large numbers of sequences and associated high-resolution structures. This is often hampered by lack of knowledge on in vivo relevant substrates. Here, we present a case study...

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Detalles Bibliográficos
Autores principales: Pinotsis, Nikos, Krüger, Anna, Tomas, Nicolas, Chatziefthymiou, Spyros D., Litz, Claudia, Mortensen, Simon Arnold, Daffé, Mamadou, Marrakchi, Hedia, Antranikian, Garabed, Wilmanns, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682391/
https://www.ncbi.nlm.nih.gov/pubmed/38012138
http://dx.doi.org/10.1038/s41467-023-43354-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682391/
https://www.ncbi.nlm.nih.gov/pubmed/38012138
http://dx.doi.org/10.1038/s41467-023-43354-4

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