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Inhibition of SF3B1 improves the immune microenvironment through pyroptosis and synergizes with αPDL1 in ovarian cancer

Ovarian cancer is resistant to immune checkpoint blockade (ICB) treatment. Combination of targeted therapy and immunotherapy is a promising strategy for ovarian cancer treatment benefit from an improved immune microenvironment. In this study, Clinical Proteomic Tumor Analysis Consortium (CPTAC) and...

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Detalles Bibliográficos
Autores principales: Wang, Shourong, Liu, Yao, Xiao, Huimin, Chen, Zhongshao, Yang, Xiaohang, Yin, Jingjing, Li, Yingwei, Yuan, Cunzhong, Yan, Shi, Chen, Gang, Gao, Qinglei, Kong, Beihua, Sun, Chaoyang, Song, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682409/
https://www.ncbi.nlm.nih.gov/pubmed/38012150
http://dx.doi.org/10.1038/s41419-023-06301-1