Optimized RT-qPCR and a novel normalization method for validating circulating miRNA biomarkers in ageing-related diseases

Circulating miRNAs have potential as minimally invasive biomarkers for diagnosing various diseases, including ageing-related disorders such as Alzheimer’s disease (AD). However, the lack of standardization in the common analysis method, RT-qPCR, and specifically in the normalization step, has result...

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Detalles Bibliográficos
Autores principales: Want, Andrew, Staniak, Karolina, Grabowska-Pyrzewicz, Wioleta, Fesiuk, Aleksandra, Barczak, Anna, Gabryelewicz, Tomasz, Kulczyńska-Przybik, Agnieszka, Mroczko, Barbara, Wojda, Urszula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682428/
https://www.ncbi.nlm.nih.gov/pubmed/38012217
http://dx.doi.org/10.1038/s41598-023-47971-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682428/
https://www.ncbi.nlm.nih.gov/pubmed/38012217
http://dx.doi.org/10.1038/s41598-023-47971-3

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