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OVOL2 sustains postnatal thymic epithelial cell identity

Distinct pathways and molecules may support embryonic versus postnatal thymic epithelial cell (TEC) development and maintenance. Here, we identify a mechanism by which TEC numbers and function are maintained postnatally. A viable missense allele (C120Y) of Ovol2, expressed ubiquitously or specifical...

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Detalles Bibliográficos
Autores principales: Zhong, Xue, Peddada, Nagesh, Wang, Jianhui, Moresco, James J., Zhan, Xiaowei, Shelton, John M., SoRelle, Jeffrey A., Keller, Katie, Lazaro, Danielle Renee, Moresco, Eva Marie Y., Choi, Jin Huk, Beutler, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682436/
https://www.ncbi.nlm.nih.gov/pubmed/38012144
http://dx.doi.org/10.1038/s41467-023-43456-z