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Predictive significance of circulating tumor DNA against patients with T790M-positive EGFR-mutant NSCLC receiving osimertinib

Circulating tumor DNA (ctDNA) provides molecular information on tumor heterogeneity. The prognostic usefulness of ctDNA after first-line epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are limited. Therefore, the present study evaluated ctDNA during osimertinib administrati...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Ou, Kasahara, Norimitsu, Soda, Hiroshi, Imai, Hisao, Naruse, Ichiro, Yamaguchi, Hiroyuki, Itai, Miki, Taguchi, Kohei, Uchida, Megumi, Sunaga, Noriaki, Maeno, Toshitaka, Minato, Koichi, Tomono, Hiromi, Ogawara, Daiki, Mukae, Hiroshi, Miura, Yu, Shiono, Ayako, Mouri, Atsuto, Kagamu, Hiroshi, Kaira, Kyoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682450/
https://www.ncbi.nlm.nih.gov/pubmed/38012343
http://dx.doi.org/10.1038/s41598-023-48210-5