Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer

Understanding the complex background of cancer requires genotype-phenotype information in single-cell resolution. Here, we perform long-read single-cell RNA sequencing (scRNA-seq) on clinical samples from three ovarian cancer patients presenting with omental metastasis and increase the PacBio sequen...

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Detalles Bibliográficos
Autores principales: Dondi, Arthur, Lischetti, Ulrike, Jacob, Francis, Singer, Franziska, Borgsmüller, Nico, Coelho, Ricardo, Heinzelmann-Schwarz, Viola, Beisel, Christian, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682465/
https://www.ncbi.nlm.nih.gov/pubmed/38012143
http://dx.doi.org/10.1038/s41467-023-43387-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682465/
https://www.ncbi.nlm.nih.gov/pubmed/38012143
http://dx.doi.org/10.1038/s41467-023-43387-9

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