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Benefit of using interaction effects for the analysis of high-dimensional time-response or dose-response data for two-group comparisons

High throughput RNA sequencing experiments are widely conducted and analyzed to identify differentially expressed genes (DEGs). The statistical models calculated for this task are often not clear to practitioners, and analyses may not be optimally tailored to the research hypothesis. Often, interact...

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Detalles Bibliográficos
Autores principales: Duda, Julia C., Drenda, Carolin, Kästel, Hue, Rahnenführer, Jörg, Kappenberg, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682470/
https://www.ncbi.nlm.nih.gov/pubmed/38012163
http://dx.doi.org/10.1038/s41598-023-47057-0