Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction

The classical Non-Homologous End Joining (c-NHEJ) pathway is the predominant process in mammals for repairing endogenous, accidental or programmed DNA Double-Strand Breaks. c-NHEJ is regulated by several accessory factors, post-translational modifications, endogenous chemical agents and metabolites....

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Detalles Bibliográficos
Autores principales: Kefala Stavridi, Antonia, Gontier, Amandine, Morin, Vincent, Frit, Philippe, Ropars, Virginie, Barboule, Nadia, Racca, Carine, Jonchhe, Sagun, Morten, Michael J, Andreani, Jessica, Rak, Alexey, Legrand, Pierre, Bourand-Plantefol, Alexa, Hardwick, Steven W, Chirgadze, Dimitri Y, Davey, Paul, De Oliveira, Taiana Maia, Rothenberg, Eli, Britton, Sebastien, Calsou, Patrick, Blundell, Tom L, Varela, Paloma F, Chaplin, Amanda K, Charbonnier, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682503/
https://www.ncbi.nlm.nih.gov/pubmed/37870477
http://dx.doi.org/10.1093/nar/gkad863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682503/
https://www.ncbi.nlm.nih.gov/pubmed/37870477
http://dx.doi.org/10.1093/nar/gkad863

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