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Effectiveness of anti-erythropoietin producing Hepatocellular receptor Type-A2 antibody in pancreatic cancer treatment

Erythropoietin-producing hepatocyte receptor type A2 (EphA2) is a tyrosine kinase that binds to ephrins (e.g., ephrin-A1) to initiate bidirectional signaling between cells. The binding of EphA2 and ephrin-A1 leads to the inhibition of Ras-MAPK activity and tumor growth. During tumorigenesis, the nor...

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Detalles Bibliográficos
Autores principales: Chang, Fu-Ling, Tsai, Keng-Chang, Lin, Tsai-Yu, Chiang, Chen-Wei, Pan, Shiow-Lin, Lee, Yu-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682614/
https://www.ncbi.nlm.nih.gov/pubmed/38034633
http://dx.doi.org/10.1016/j.heliyon.2023.e21774