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Revisiting bacterial cytolethal distending toxin structure and function

Cytolethal distending toxins (CDTs) are intracellular-acting bacterial genotoxins generated by a diverse group of mucocutaneous human pathogens. CDTs must successfully bind to the plasma membrane of host cells in order to exert their modulatory effects. Maximal toxin activity requires all three toxi...

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Detalles Bibliográficos
Autores principales: Chen, Henry, Ang, Claire J., Crowder, Molly, Brieher, William M., Blanke, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682658/
https://www.ncbi.nlm.nih.gov/pubmed/38035327
http://dx.doi.org/10.3389/fcimb.2023.1289359