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Oral cannabidiol (CBD) as add-on to paracetamol for painful chronic osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trial

BACKGROUND: Painful knee osteoarthritis (KOA) is common, pharmacological treatment, however, is often hampered by limited tolerability. Cannabidiol, which preclinically showed anti-inflammatory, analgesic activity, could supplement established analgesics, but robust clinical trials are lacking. The...

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Detalles Bibliográficos
Autores principales: Pramhas, Sibylle, Thalhammer, Teresa, Terner, Sebastian, Pickelsberger, Daniel, Gleiss, Andreas, Sator, Sabine, Kress, Hans G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682664/
https://www.ncbi.nlm.nih.gov/pubmed/38033459
http://dx.doi.org/10.1016/j.lanepe.2023.100777