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Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus

INTRODUCTION: Status epilepticus (SE) can significantly increase the risk of temporal lobe epilepsy (TLE) and cognitive comorbidities. A potential candidate mechanism underlying memory defects in epilepsy may be the immune complement system. The complement cascade, part of the innate immune system,...

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Detalles Bibliográficos
Autores principales: Schartz, Nicole D., Aroor, Alisha, Li, Yibo, Pinzón-Hoyos, Nicole, Brewster, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682718/
https://www.ncbi.nlm.nih.gov/pubmed/38035266
http://dx.doi.org/10.3389/fnmol.2023.1265944