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Mice deficient in complement C3 are protected against recognition memory deficits and astrogliosis induced by status epilepticus
INTRODUCTION: Status epilepticus (SE) can significantly increase the risk of temporal lobe epilepsy (TLE) and cognitive comorbidities. A potential candidate mechanism underlying memory defects in epilepsy may be the immune complement system. The complement cascade, part of the innate immune system,...
Autores principales: | Schartz, Nicole D., Aroor, Alisha, Li, Yibo, Pinzón-Hoyos, Nicole, Brewster, Amy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682718/ https://www.ncbi.nlm.nih.gov/pubmed/38035266 http://dx.doi.org/10.3389/fnmol.2023.1265944 |
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