The activity of a PI3K δ-sparing inhibitor, MEN1611, in non-small cell lung cancer cells with constitutive activation of the PI3K/AKT/mTOR pathway

BACKGROUND: Lung cancer remains the leading cause of cancer-related death worldwide. Targeted therapies with tyrosine kinase inhibitors (TKIs) result in improvement in survival for non-small cell lung cancer (NSCLC) with activating mutations of the epidermal growth factor receptor (EGFR). Unfortunat...

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Detalles Bibliográficos
Autores principales: Papoff, Giuliana, Presutti, Dario, Fustaino, Valentina, Parente, Andrea, Calandriello, Clelia, Alemà, Stefano, Scavizzi, Ferdinando, Raspa, Marcello, Merlino, Giuseppe, Salerno, Massimiliano, Bigioni, Mario, Binaschi, Monica, Ruberti, Giovina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682785/
https://www.ncbi.nlm.nih.gov/pubmed/38033496
http://dx.doi.org/10.3389/fonc.2023.1283951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682785/
https://www.ncbi.nlm.nih.gov/pubmed/38033496
http://dx.doi.org/10.3389/fonc.2023.1283951

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