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Cryo-EM structure of the trehalose monomycolate transporter, MmpL3, reconstituted into peptidiscs

Mycobacteria have an atypical thick and waxy cell wall. One of the major building blocks of such mycomembrane is trehalose monomycolate (TMM). TMM is a mycolic acid ester of trehalose that possesses long acyl chains with up to 90 carbon atoms. TMM represents an essential component of mycobacteria an...

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Detalles Bibliográficos
Autores principales: Couston, Julie, Guo, Zongxin, Wang, Kaituo, Gourdon, Pontus, Blaise, Mickaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682824/
https://www.ncbi.nlm.nih.gov/pubmed/38034087
http://dx.doi.org/10.1016/j.crstbi.2023.100109