Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application

In this study, The inhibitory actions of human carbonic anhydrase (CA, EC 4.2.1.1) (hCA) isoforms I, II, IX, and XII are being examined using recently synthesized substituted hydroxyl Schiff derivatives based on the quinazoline scaffold 4–22. Quinazolines 2, 3, 4, 5, 7, 10, 15, and 18 reduce the act...

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Detalles Bibliográficos
Autores principales: El-Azab, Adel S., A.-M. Abdel-Aziz, Alaa, Bua, Silvia, Nocentini, Alessio, Bakheit, Ahmed H., Alkahtani, Hamad M., Hefnawy, Mohamed M., Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682911/
https://www.ncbi.nlm.nih.gov/pubmed/38033749
http://dx.doi.org/10.1016/j.jsps.2023.101866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682911/
https://www.ncbi.nlm.nih.gov/pubmed/38033749
http://dx.doi.org/10.1016/j.jsps.2023.101866

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