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Treatment of Parkinson’s disease with biologics that penetrate the blood–brain barrier via receptor-mediated transport
Parkinson’s disease (PD) is characterized by neurodegeneration of nigral-striatal neurons in parallel with the formation of intra-neuronal α-synuclein aggregates, and these processes are exacerbated by neuro-inflammation. All 3 components of PD pathology are potentially treatable with biologics. Neu...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682952/ https://www.ncbi.nlm.nih.gov/pubmed/38035276 http://dx.doi.org/10.3389/fnagi.2023.1276376 |