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Carvedilol impairs bile acid homeostasis in mice: implication for nonalcoholic steatohepatitis

Carvedilol is a widely used beta-adrenoreceptor antagonist for multiple cardiovascular indications; however, it may induce cholestasis in patients, but the mechanism for this effect is unclear. Carvedilol also prevents the development of various forms of experimental liver injury, but its effect on...

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Detalles Bibliográficos
Autores principales: Lastuvkova, Hana, Nova, Zuzana, Hroch, Milos, Alaei Faradonbeh, Fatemeh, Schreiberova, Jolana, Mokry, Jaroslav, Faistova, Hana, Stefela, Alzbeta, Dusek, Jan, Kucera, Otto, Hyspler, Radomír, Dohnalkova, Ester, Bayer, Rachel L, Hirsova, Petra, Pavek, Petr, Micuda, Stanislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10682974/
https://www.ncbi.nlm.nih.gov/pubmed/37632784
http://dx.doi.org/10.1093/toxsci/kfad088