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Exploring Fatty Acid Mimetics as NR4A Ligands

[Image: see text] The ligand-activated transcription factors Nur77, Nurr1, and NOR-1 forming the NR4A family of nuclear receptors are considered as potential targets in various pathologies, including neurodegeneration and cancer. However, chemical tools for pharmacological NR4A modulation as a prere...

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Detalles Bibliográficos
Autores principales: Stiller, Tanja, Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683012/
https://www.ncbi.nlm.nih.gov/pubmed/37918435
http://dx.doi.org/10.1021/acs.jmedchem.3c01467