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Reversal of mitochondrial permeability transition pore and pancreas degeneration by chloroform fraction of Ocimum gratissimum (L.) leaf extract in type 2 diabetic rat model

Introduction: Unmanaged Diabetes Mellitus (DM) usually results to tissue wastage because of mitochondrial dysfunction. Adverse effects of some drugs used in the management of DM necessitates the search for alternative therapy from plant origin with less or no side effects. Ocimum gratissimum (L.) (O...

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Detalles Bibliográficos
Autores principales: Salemcity, A. J., Olanlokun, John Oludele, Olowofolahan, A. O., Olojo, F. O., Adegoke, Ayodeji Mathias, Olorunsogo, O. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683093/
https://www.ncbi.nlm.nih.gov/pubmed/38035005
http://dx.doi.org/10.3389/fphar.2023.1231826