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Effects of a single dose of amisulpride on functional brain changes during reward- and motivation-related processing using task-based fMRI in healthy subjects and patients with major depressive disorder — study protocol for a randomized clinical trial

BACKGROUND: Anhedonia and other deficits in reward- and motivation-related processing in psychiatric patients, including patients with major depressive disorder (MDD), represent a high unmet medical need. Neurobiologically, these deficits in MDD patients are mainly associated with low dopamine funct...

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Detalles Bibliográficos
Autores principales: Carstens, Luisa, Popp, Margot, Keicher, Christian, Hertrampf, Rita, Weigner, David, Meiering, Marvin S., Luippold, Gerd, Süssmuth, Sigurd D., Beckmann, Christian F., Wunder, Andreas, Grimm, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683198/
https://www.ncbi.nlm.nih.gov/pubmed/38012795
http://dx.doi.org/10.1186/s13063-023-07788-x