Extracellular vesicle-packaged circBIRC6 from cancer-associated fibroblasts induce platinum resistance via SUMOylation modulation in pancreatic cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) play pivotal roles in chemoresistance of pancreatic ductal adenocarcinoma (PDAC). However, the underlying mechanisms are poorly understood. Revealing the cross-talk network between tumor stroma and pancreatic cancer and developing effective strategies...

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Detalles Bibliográficos
Autores principales: Zheng, Shangyou, Tian, Qing, Yuan, Yuan, Sun, Shuxin, Li, Tingting, Xia, Renpeng, He, Rihua, Luo, Yuming, Lin, Qing, Fu, Zhiqiang, Zhou, Yu, Chen, Rufu, Hu, Chonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683239/
https://www.ncbi.nlm.nih.gov/pubmed/38012734
http://dx.doi.org/10.1186/s13046-023-02854-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683239/
https://www.ncbi.nlm.nih.gov/pubmed/38012734
http://dx.doi.org/10.1186/s13046-023-02854-3

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