N6-methyladenosine-modified circRIMS2 mediates synaptic and memory impairments by activating GluN2B ubiquitination in Alzheimer's disease

BACKGROUND: Synaptic degeneration occurs in the early stage of Alzheimer's disease (AD) before devastating symptoms, strongly correlated with cognitive decline. Circular RNAs (circRNAs) are abundantly enriched in neural tissues, and aberrant expression of circRNAs precedes AD symptoms, signific...

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Detalles Bibliográficos
Autores principales: Wang, Xiong, Xie, Jiazhao, Tan, Lu, Lu, Yanjun, Shen, Na, Li, Jiaoyuan, Hu, Hui, Li, Huijun, Li, Xiaoguang, Cheng, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683276/
https://www.ncbi.nlm.nih.gov/pubmed/38012808
http://dx.doi.org/10.1186/s40035-023-00386-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683276/
https://www.ncbi.nlm.nih.gov/pubmed/38012808
http://dx.doi.org/10.1186/s40035-023-00386-6

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