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Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study

BACKGROUND: Post-radiation nasopharyngeal necrosis (PRNN) is a severe adverse event following re-radiotherapy for patients with locally recurrent nasopharyngeal carcinoma (LRNPC) and associated with decreased survival. Biological heterogeneity in recurrent tumors contributes to the different risks o...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Dong, Di, Zhao, Xun, Ou, Xiao-Min, Yi, Jun-Lin, Guan, Jian, Zhang, Ye, Xiao-Fei, Lv, Xie, Chuan-Miao, Luo, Dong-Hua, Sun, Rui, Chen, Qiu-Yan, Xing, Lv, Guo, Shan-Shan, Liu, Li-Ting, Lin, Da-Feng, Chen, Yan-Zhou, Lin, Jie-Yi, Luo, Mei-Juan, Yan, Wen-Bin, He, Mei-Lin, Mao, Meng-Yuan, Zhu, Man-Yi, Chen, Wen-Hui, Shen, Bo-Wen, Wang, Shi-Qian, Li, Hai-Lin, Zhong, Lian-Zhen, Hu, Chao-Su, Wu, De-Hua, Mai, Hai-Qiang, Tian, Jie, Tang, Lin-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683300/
https://www.ncbi.nlm.nih.gov/pubmed/38012705
http://dx.doi.org/10.1186/s12916-023-03164-3