Modular bioengineering of whole-cell catalysis for sialo-oligosaccharide production: coordinated co-expression of CMP-sialic acid synthetase and sialyltransferase

BACKGROUND: In whole-cell bio-catalysis, the biosystems engineering paradigm shifts from the global reconfiguration of cellular metabolism as in fermentation to a more focused, and more easily modularized, optimization of comparably short cascade reactions. Human milk oligosaccharides (HMO) constitu...

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Detalles Bibliográficos
Autores principales: Schelch, Sabine, Eibinger, Manuel, Zuson, Jasmin, Kuballa, Jürgen, Nidetzky, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683312/
https://www.ncbi.nlm.nih.gov/pubmed/38012629
http://dx.doi.org/10.1186/s12934-023-02249-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683312/
https://www.ncbi.nlm.nih.gov/pubmed/38012629
http://dx.doi.org/10.1186/s12934-023-02249-1

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