Cargando…

Application of Raman Spectroscopy to Dynamic Binding Capacity Analysis

Protein A affinity chromatography is a key step in isolation of biotherapeutics (BTs) containing fragment crystallizable regions, including monoclonal and bispecific antibodies. Dynamic binding capacity (DBC) analysis assesses how much BT will bind to a protein A column. DBC reduces with column usag...

Descripción completa

Detalles Bibliográficos
Autores principales: Beattie, James W., Rowland-Jones, Ruth C., Farys, Monika, Bettany, Hamish, Hilton, David, Kazarian, Sergei G., Byrne, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683347/
https://www.ncbi.nlm.nih.gov/pubmed/37908083
http://dx.doi.org/10.1177/00037028231210293