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Application of Raman Spectroscopy to Dynamic Binding Capacity Analysis

Protein A affinity chromatography is a key step in isolation of biotherapeutics (BTs) containing fragment crystallizable regions, including monoclonal and bispecific antibodies. Dynamic binding capacity (DBC) analysis assesses how much BT will bind to a protein A column. DBC reduces with column usag...

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Detalles Bibliográficos
Autores principales:	Beattie, James W., Rowland-Jones, Ruth C., Farys, Monika, Bettany, Hamish, Hilton, David, Kazarian, Sergei G., Byrne, Bernadette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Submitted Manuscripts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683347/ https://www.ncbi.nlm.nih.gov/pubmed/37908083 http://dx.doi.org/10.1177/00037028231210293

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