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hnRNPA2B1 promotes the occurrence and progression of hepatocellular carcinoma by downregulating PCK1 mRNA via a m6A RNA methylation manner

BACKGROUND: N6-methyladenosine (m6A) is the most prevalent RNA modification. Although hnRNPA2B1, as a reader of m6A modification, has been reported to promote tumorigenesis in a few types of tumors, its role in hepatocellular carcinoma (HCC) and the underlying molecular mechanism remains unclear. ME...

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Detalles Bibliográficos
Autores principales: Hao, Weijie, Chen, Zhimin, Tang, Jingzhi, Yang, Ru, Gao, Wei-Qiang, Xu, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683354/
https://www.ncbi.nlm.nih.gov/pubmed/38017546
http://dx.doi.org/10.1186/s12967-023-04704-4