A Novel Natural Siderophore Antibiotic Conjugate Reveals a Chemical Approach to Macromolecule Coupling

[Image: see text] Inspired by natural sideromycins, the conjugation of antibiotics to siderophores is an attractive strategy to facilitate “Trojan horse” delivery of antibiotics into bacteria. Genome analysis of a soil bacterium, Dactylosporangium fulvum, found a “hybrid” biosynthetic gene cluster r...

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Detalles Bibliográficos
Autores principales: Caradec, Thibault, Anoz-Carbonell, Ernesto, Petrov, Ravil, Billamboz, Muriel, Antraygues, Kevin, Cantrelle, Francois-Xavier, Boll, Emmanuelle, Beury, Delphine, Hot, David, Drobecq, Herve, Trivelli, Xavier, Hartkoorn, Ruben C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683483/
https://www.ncbi.nlm.nih.gov/pubmed/38033789
http://dx.doi.org/10.1021/acscentsci.3c00965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683483/
https://www.ncbi.nlm.nih.gov/pubmed/38033789
http://dx.doi.org/10.1021/acscentsci.3c00965

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