Clinically Translatable Hyperpolarized (13)C Bicarbonate pH Imaging Method for Use in Prostate Cancer

[Image: see text] Solid tumors such as prostate cancer (PCa) commonly develop an acidic microenvironment with pH 6.5–7.2, owing to heterogeneous perfusion, high metabolic activity, and rapid cell proliferation. In preclinical prostate cancer models, disease progression is associated with a decrease...

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Detalles Bibliográficos
Autores principales: Mu, Changhua, Liu, Xiaoxi, Kim, Yaewon, Riselli, Andrew, Korenchan, David E., Bok, Robert A., Delos Santos, Romelyn, Sriram, Renuka, Qin, Hecong, Nguyen, Hao, Gordon, Jeremy W., Slater, James, Larson, Peder E. Z., Vigneron, Daniel B., Kurhanewicz, John, Wilson, David M., Flavell, Robert R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683509/
https://www.ncbi.nlm.nih.gov/pubmed/37878761
http://dx.doi.org/10.1021/acssensors.3c00851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683509/
https://www.ncbi.nlm.nih.gov/pubmed/37878761
http://dx.doi.org/10.1021/acssensors.3c00851

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