High-mobility group box-1 impedes skeletal muscle regeneration via downregulation of Pax-7 synthesis by increasing miR-342-5p expression

High mobility group box-1 (HMGB1) is a driver of inflammation in various muscular diseases. In a previous study, we determined that HMGB1 induced the atrophy of skeletal muscle by impairing myogenesis. Skeletal muscle regeneration after injury is dependent on pair box 7 (Pax-7)-mediated myogenic dif...

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Detalles Bibliográficos
Autores principales: Ho, Trung-Loc, Lai, Yu-Liang, Hsu, Chin-Jung, Su, Chen-Ming, Tang, Chih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683625/
https://www.ncbi.nlm.nih.gov/pubmed/37963838
http://dx.doi.org/10.18632/aging.205202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683625/
https://www.ncbi.nlm.nih.gov/pubmed/37963838
http://dx.doi.org/10.18632/aging.205202

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