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Endothelial nitric oxide synthase (eNOS) S1176 phosphorylation status governs atherosclerotic lesion formation

OBJECTIVE: We have previously demonstrated the in vivo importance of the Akt-eNOS substrate-kinase relationship, as defective postnatal angiogenesis characteristic of global Akt1-null mice is rescued when bred to ‘gain-of-function’ eNOS S1176D mutant mice. While multiple studies support the vascular...

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Detalles Bibliográficos
Autores principales: Nguyen, Tung D., Rahman, Nur-Taz, Sessa, William C., Lee, Monica Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683645/
https://www.ncbi.nlm.nih.gov/pubmed/38034389
http://dx.doi.org/10.3389/fcvm.2023.1279868