Investigation of genomic mutations and their association with phenotypic resistance to new and repurposed drugs in Mycobacterium tuberculosis complex clinical isolates

BACKGROUND: WGS has the potential to detect resistance-associated mutations and guide treatment of MDR TB. However, the knowledge base to confidently interpret mutations associated with the new and repurposed drugs is sparse, and phenotypic drug susceptibility testing is required to detect resistanc...

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Detalles Bibliográficos
Autores principales: Mok, Simone, Roycroft, Emma, Flanagan, Peter R, Wagener, Johannes, Fitzgibbon, Margaret M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683940/
https://www.ncbi.nlm.nih.gov/pubmed/37740935
http://dx.doi.org/10.1093/jac/dkad252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683940/
https://www.ncbi.nlm.nih.gov/pubmed/37740935
http://dx.doi.org/10.1093/jac/dkad252

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