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Quantifying the Individual Variation in Susceptibility to Endemic Coronavirus and SARS-CoV-2 with Human Challenge Trials

Human challenge trials reveal how the infection risk depends on a given infectious dose. We propose a mathematical framework to analyze and interpret the outcomes of human challenge trials by incorporating the variability between individuals in susceptibility to infection. We illustrate the framewor...

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Detalles Bibliográficos
Autores principales:	Miura, Fuminari, Klinkenberg, Don, Wallinga, Jacco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Infectious Diseases
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683973/ https://www.ncbi.nlm.nih.gov/pubmed/38032803 http://dx.doi.org/10.1097/EDE.0000000000001679

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