Quantifying the Individual Variation in Susceptibility to Endemic Coronavirus and SARS-CoV-2 with Human Challenge Trials

Human challenge trials reveal how the infection risk depends on a given infectious dose. We propose a mathematical framework to analyze and interpret the outcomes of human challenge trials by incorporating the variability between individuals in susceptibility to infection. We illustrate the framewor...

Descripción completa

Detalles Bibliográficos
Autores principales: Miura, Fuminari, Klinkenberg, Don, Wallinga, Jacco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683973/
https://www.ncbi.nlm.nih.gov/pubmed/38032803
http://dx.doi.org/10.1097/EDE.0000000000001679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10683973/
https://www.ncbi.nlm.nih.gov/pubmed/38032803
http://dx.doi.org/10.1097/EDE.0000000000001679

Ejemplares similares